Paul Chaplin Selected Research

Smallpox Vaccine (Vaccine, Smallpox)

10/2021	Human Antibody Responses Following Vaccinia Immunization Using Protein Microarrays and Correlation With Cell-Mediated Immunity and Antibody-Dependent Cellular Cytotoxicity Responses.
11/2019	Phase 3 Efficacy Trial of Modified Vaccinia Ankara as a Vaccine against Smallpox.
1/2018	Immunogenicity and safety of three consecutive production lots of the non replicating smallpox vaccine MVA: A randomised, double blind, placebo controlled phase III trial.
1/2016	A Randomized, Double-Blind, Placebo-Controlled Phase II Trial Investigating the Safety and Immunogenicity of Modified Vaccinia Ankara Smallpox Vaccine (MVA-BN®) in 56-80-Year-Old Subjects.
9/2015	Comparison of lyophilized versus liquid modified vaccinia Ankara (MVA) formulations and subcutaneous versus intradermal routes of administration in healthy vaccinia-naïve subjects.
4/2015	Safety and Immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic Smallpox Vaccine in Vaccinia-Naive and Experienced Human Immunodeficiency Virus-Infected Individuals: An Open-Label, Controlled Clinical Phase II Trial.
1/2015	Correction: A Multicenter, Open-Label, Controlled Phase II Study to Evaluate Safety and Immunogenicity of MVA Smallpox Vaccine (IMVAMUNE) in 18-40 Year Old Subjects with Diagnosed Atopic Dermatitis.
1/2015	Cardiac safety of Modified Vaccinia Ankara for vaccination against smallpox in a young, healthy study population.
1/2015	A Multicenter, Open-Label, Controlled Phase II Study to Evaluate Safety and Immunogenicity of MVA Smallpox Vaccine (IMVAMUNE) in 18-40 Year Old Subjects with Diagnosed Atopic Dermatitis.
9/2014	Safety and immunogenicity of modified vaccinia Ankara as a smallpox vaccine in people with atopic dermatitis.

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Paul Chaplin Research Topics

Disease

24	Vaccinia 10/2021 - 03/2003
11	Smallpox (Variola) 01/2020 - 03/2006
7	Neoplasms (Cancer) 01/2021 - 08/2004
4	Infections 11/2019 - 09/2010
3	Virus Diseases (Viral Diseases) 01/2020 - 12/2014
3	Communicable Diseases (Infectious Diseases) 01/2017 - 05/2006
3	Atopic Dermatitis (Atopic Eczema) 01/2015 - 09/2014
3	Melanoma (Melanoma, Malignant) 05/2005 - 09/2003
1	Respiratory Syncytial Virus Infections 01/2022
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2020
1	Measles 01/2018
1	Necrosis 01/2018
1	Fever (Fevers) 01/2017
1	Ebola Hemorrhagic Fever 01/2017
1	Vesicular Stomatitis 04/2016
1	Kaposi Varicelliform Eruption (Eczema Herpeticum) 09/2014
1	Cowpox 05/2006
1	Human Influenza (Influenza) 03/2003

Drug/Important Bio-Agent (IBA)

20	VaccinesIBA 10/2021 - 03/2006
12	Smallpox Vaccine (Vaccine, Smallpox)FDA Link 10/2021 - 02/2010
8	smallpox and monkeypox vaccine modified vaccinia ankara-bavarian nordicIBA 01/2020 - 03/2006
6	AntigensIBA 10/2021 - 08/2004
5	Proteins (Proteins, Gene)FDA Link 10/2021 - 09/2010
3	AntibodiesIBA 10/2021 - 01/2015
3	Viral VaccinesIBA 01/2018 - 01/2013
3	Monophenol Monooxygenase (Tyrosinase)IBA 05/2005 - 09/2003
2	Respiratory Syncytial Virus VaccinesIBA 01/2022 - 01/2020
2	LigandsIBA 01/2021 - 01/2018
2	MVA vaccineIBA 11/2019 - 03/2003
2	ImmunosorbentsIBA 01/2018 - 01/2016
2	EnzymesIBA 01/2018 - 01/2016
2	Glycoproteins (Glycoprotein)IBA 01/2017 - 04/2016
2	Neutralizing AntibodiesIBA 04/2016 - 05/2014
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2021
1	ACAM2000IBA 11/2019
1	CD40 Ligand (CD40L)IBA 11/2019
1	Fc Receptors (Fc Receptor)IBA 11/2019
1	FlagellinIBA 01/2017
1	NucleoproteinsIBA 01/2017
1	Protein Kinases (Protein Kinase)IBA 12/2014
1	Double-Stranded RNA (RNA, Double Stranded)IBA 12/2014
1	Interferon Type IIBA 12/2014
1	Biomarkers (Surrogate Marker)IBA 03/2013
1	Viral DNAIBA 09/2010
1	Complex MixturesIBA 12/2009
1	Biological ProductsIBA 12/2009
1	Intergenic DNA (Junk DNA)IBA 05/2006
1	Synthetic Vaccines (Recombinant Vaccines)IBA 05/2006
1	Peptides (Polypeptides)IBA 03/2003
1	DNA (Deoxyribonucleic Acid)IBA 03/2003

Therapy/Procedure

3	Immunotherapy 01/2021 - 08/2004
3	Therapeutics 11/2019 - 05/2005
2	Subcutaneous Injections 01/2016 - 01/2015